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Dietmar Abraham Selected Research

Macrophage Colony-Stimulating Factor

5/2018Differential prognostic impact of interleukin-34 mRNA expression and infiltrating immune cell composition in intrinsic breast cancer subtypes.
3/2010Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma.
8/2008Colony-stimulating factor-1 transfection of myoblasts improves the repair of failing myocardium following autologous myoblast transplantation.
5/2008Modulation of tumor associated macrophages in solid tumors.
2/2007Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway.
1/2007Target validation using RNA interference in solid tumors.
4/2006Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts.
8/2004Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.
9/2002Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice.

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Dietmar Abraham Research Topics

Disease

20Neoplasms (Cancer)
01/2020 - 01/2002
6Neoplasm Metastasis (Metastasis)
01/2020 - 10/2003
5Breast Neoplasms (Breast Cancer)
05/2018 - 08/2004
4Myocardial Infarction
10/2021 - 08/2008
4Cardiomyopathies (Cardiomyopathy)
01/2021 - 09/2003
4Hypoxia (Hypoxemia)
01/2019 - 05/2002
4Neuroblastoma
09/2016 - 01/2002
4Colonic Neoplasms (Colon Cancer)
11/2013 - 09/2002
3Fibrosis (Cirrhosis)
12/2020 - 05/2004
3Carcinoma (Carcinomatosis)
09/2013 - 09/2002
3Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
06/2010 - 09/2003
2Myocardial Ischemia (Ischemic Heart Diseases)
01/2019 - 01/2019
2Hypertrophy
01/2019 - 01/2018
2Prostatic Neoplasms (Prostate Cancer)
09/2013 - 01/2013
2Heart Failure
05/2011 - 08/2008
2Acute Lung Injury
05/2004 - 06/2002
2Nonseminomatous germ cell tumor
10/2003 - 01/2002
2Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
10/2003 - 01/2002
1Cardiovascular Abnormalities
01/2021
1Mitral Valve Insufficiency (Mitral Regurgitation)
12/2020
1Ventilator-Induced Lung Injury
03/2019
1Inflammation (Inflammations)
01/2019
1Ventricular Remodeling
01/2019
1Genomic Instability
12/2015
1Colorectal Neoplasms (Colorectal Cancer)
11/2013
1Ischemia
09/2009
1Infarction (Infarctions)
08/2008

Drug/Important Bio-Agent (IBA)

13Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2016 - 01/2002
9Macrophage Colony-Stimulating FactorIBA
05/2018 - 09/2002
8Matrix Metalloproteinases (MMPs)IBA
01/2018 - 09/2002
7Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2020 - 01/2007
7Metalloproteases (Metalloproteinases)IBA
08/2008 - 08/2004
6Messenger RNA (mRNA)IBA
05/2018 - 01/2002
5CytokinesIBA
01/2020 - 01/2007
4Small Interfering RNA (siRNA)IBA
01/2020 - 02/2007
4Proteins (Proteins, Gene)FDA Link
01/2013 - 09/2002
4Ringer's SolutionIBA
05/2011 - 01/2002
3TenascinIBA
12/2020 - 01/2018
2salicylhydroxamic acid (SHAM)IBA
01/2019 - 10/2003
2DNA (Deoxyribonucleic Acid)IBA
01/2019 - 05/2004
2rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA
11/2013 - 01/2013
2GTP Phosphohydrolases (GTPases)IBA
11/2013 - 01/2013
2AndrogensIBA
09/2013 - 01/2013
2Colony-Stimulating Factors (Colony Stimulating Factor)IBA
02/2007 - 01/2007
2Antisense OligonucleotidesIBA
08/2004 - 09/2002
2Macrophage Colony-Stimulating Factor Receptor (Receptor, Macrophage Colony Stimulating Factor)IBA
08/2004 - 09/2002
2Carboplatin (JM8)FDA LinkGeneric
10/2003 - 01/2002
1DystrophinIBA
01/2021
1Glycoproteins (Glycoprotein)IBA
12/2020
1PlasticsIBA
01/2020
1ChemokinesIBA
01/2020
1Neuregulin-1 (Neuregulin 1)IBA
01/2019
1MicroRNAs (MicroRNA)IBA
01/2019
1Phenobarbital (Luminal)FDA Link
05/2018
1Tyrosine (L-Tyrosine)FDA Link
05/2018
1Atrial Natriuretic Factor (ANF)IBA
01/2018
1CateninsIBA
07/2016
1RecQ HelicasesIBA
12/2015
1Peptide Hydrolases (Proteases)FDA Link
01/2015
1Aromatase (CYP19)IBA
01/2014
13' Untranslated Regions (3' UTR)IBA
01/2014
1Pharmaceutical PreparationsIBA
11/2013
1N2- (4- diethylamino- 1- methylbutyl)- N4- (2- (1H- indol- 3- yl)ethyl)- 6- methylpyrimidine- 2,4- diamineIBA
11/2013
1Therapeutic UsesIBA
11/2013
1Cyclin D1IBA
01/2013
1Carrier Proteins (Binding Protein)IBA
06/2010
1Tissue Plasminogen Activator (Alteplase)FDA Link
06/2010
1Plasminogen Activators (Plasminogen Activator)IBA
06/2010
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
06/2010
1Plasminogen Activator Inhibitor 1IBA
06/2010
1Urokinase Plasminogen Activator ReceptorsIBA
06/2010
1Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA
05/2008
1Cell Adhesion MoleculesIBA
05/2008
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2007
1Biological ProductsIBA
01/2007
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
04/2006
1ceramide glucosyltransferaseIBA
04/2006
1Methotrexate (Mexate)FDA LinkGeneric
04/2006
1AntigensIBA
04/2006
1Fluorouracil (Carac)FDA LinkGeneric
04/2006
1Immunoglobulin Fab FragmentsIBA
04/2006
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
04/2006
1AntibodiesIBA
04/2006
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
04/2006
1Transforming Growth Factors (Transforming Growth Factor)IBA
09/2005
1Endothelins (Endothelin)IBA
09/2005
1CollagenIBA
09/2005
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
09/2005

Therapy/Procedure

8Therapeutics
01/2021 - 01/2002
5Transplantation
06/2010 - 06/2002
3Injections
05/2011 - 08/2004
2Ligation
10/2021 - 01/2019
2Aftercare (After-Treatment)
11/2013 - 01/2002
2Lung Transplantation
05/2004 - 05/2002
2Drug Therapy (Chemotherapy)
10/2003 - 01/2002
1Immunotherapy
01/2020
1Artificial Respiration (Mechanical Ventilation)
03/2019
1RNAi Therapeutics
01/2015
1Heart Transplantation (Grafting, Heart)
06/2010
1Combination Drug Therapy (Combination Chemotherapy)
04/2006